Non Surgical Treatment

Efudix (5-flurouracil)
Efudix is commonly used for the treatment of actinic keratosis.
The cream is made from a chemotherapeutic agent that when applied to skin is taken up by pre-cancerous and cancer cells, resulting in cell destruction. The cream also irritates normal skin and therefore results in significant inflammation during treatment. The reaction on the skin can vary from mild to severe redness and crusting.

Imiquimod (Aldara)
Aldara is a cream that works for selected skin cancer including some superficial basal cell cancers. The cream works by stimulating the immune system to recognise and subsequently destroy the cancer cells. As the cream stimulates the immune system, it is not unusual that skin in the surrounding area also becomes inflamed. The degree of inflammation varies between patients, and can vary from mild to severe.

Radiotherapy can be used for a wide variety of skin cancers as either a primary treatment or often as an adjunctive treatment to surgery in order to maximise cure rate. Radiotherapy works by directing radiation at a target area, subsequently destroying cancer cells. The treatment is aimed at killing cancer cells but normal cells will also be affected, often resulting in significant inflammation at the treatment site.

The effectiveness of Radiation will vary depending on factors including the skin cancer type, site, extent and radiation used. Not all tumours respond to radiotherapy, and cancers such as melanoma are not regarded as very sensitive to this management. In certain anatomical sites, such as the lower leg, radiotherapy is best avoided.
This treatment requires referral to a Specialist Radiation Clinic.


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